"We have not co-evolved with these species," WCS's Dr. Christian Walzer tells podcast host Bill Nye regarding wildlife found in markets, "so we have not had thousands of years to acquire these diseases, build antibodies against them or make them uniquely our own." This gives such novel pathogens in humans greater pandemic potential. Combined with the co-mixing of multiple species and often stressful conditions along market trade chains, these unnatural interfaces between live wildlife, domestic animals and humans provide ideal conditions for spillover. Learn more on how spillover happens in Bill Nye's podcast with Dr Walzer:
Coronavirus: Do Cry Over Spillovers